Brazil’s Jose Adilson Rodrigues Dos Santos, “Maguila”, has died aged 66.

The former opponent of, among others, Evander Holyfield and George Foreman reportedly suffered with health complications from suspected chronic traumatic encephalopathy.

He fought 85 times over the course of 17 years, winning 77 of those fights – 68 by knockout – and reigned as the Brazilian and South American heavyweight champion.

Maguila retired in 2000, and it was in 2013 when he was diagnosed with CTE, having by then struggled with memory loss and confusion. The aggressive behavior often associated with his condition contributed to his wife Irani Pinheiro pursuing professional help.

It was in 2018 when he elected to donate his brain to scientific research after his death. The final years of his life were spent at the Anjos de Deus Therapeutic Center in Itu, Sao Paulo.