I gave Ricky a reet good hiding t'other day.
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Limey Lang
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The whole world is gonna find out how our boxers are so fantastic at this rate.
******* makes us go harder for longer.
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a1A-Adrenergic antagonists
Alfuzosin: 1st-line treatment for BPH, no cardiovascular (anti-hypertensive) activity. Metabolized by 7-O-demethylation and N-dealkylation to inactive metabolites. Dose reduction required for patients with hepatic insufficiency
Doxazosin: metabolized by 7-O-demethylation, aromatic hydroxylation (other aromatic ring) and piperazine ring oxidation to inactive metabolites
Terazosin: 6-, and 7-O-demethylation and N-dealkylation yields 4 inactive metabolites
Tamsulosin: also 1st-line for BPH because of uroselectivity. O-demethylated and oxidized at position 3 to metabolites that are glucuronidated or sulphated prior to renal clearance
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